Scientists Remove PreDiabetes In Mice

As the years have progressed, science and its profound miracles have eradicated the majority of life-threatening diseases. Most of the credit goes to brilliant minds and the vaccines that they enabled for others. However, there is still a wide class of diseases that have bothered humanity from time immemorial. Diabetes is one of them.

Unlike the mainstream course of normal diseases, diabetes isn’t contagious. You can’t pass it on to the person next to you. You either have it, or you don’t. However, if you don’t, that doesn’t mean you’re entirely safe from it because unlike other diseases, you do have a say on if you get diabetes later on or not.

What are the two types of diabetes?

Diabetes is of two types: Type 1 and type 2. Type 1 can be contracted due to poor dietary practices and lifestyle. Diets rich in oils and fats are often linked as the major cause for this, which is why it often occurs later in life. Type 2, however, is due to hereditary reasons. The symptoms might be there for the beginning or start to show later on.

Mice and diabetes

As far as genetics go, mice and humans are without a doubt quite similar. The reason mice are chosen for these particular tests is that they show a response to external stimuli quicker than humans. Furthermore, this is accentuated by their short lifespan in which scientist can observe genetic manipulation and particular side-effects. As far as diabetes goes, scientists can observe symptoms and the effect experimentation have on them throughout the mice’s lifetime.

Is there a cure?

Due to its prevalence in modern day society, scientists are working tirelessly day and night to find the long-awaited cure for diabetes. In that regard, there hasn’t been much success. Granted that there are medicines to stabilize things for a little while, but no breakthroughs have been made recently, until now.

Scientists at the University of Utah Health and Merck Research Laboratories published a paper a few days back that gave an interesting insight into the biological roots and behavior of the underlying causes of diabetes.  The breakthrough came from altering the position of two hydrogen atoms, which the scientists claim is the major difference between healthy mice and one with severe symptoms.

This removal led to the reduction in the production of the enzyme dihydroceramide desaturase 1 (DES1). Doing so led to a significant lowering of the number of ceramides in the body. Since then, scientists have debated that ceramides are perhaps a pivotal factor in a lot of metabolic diseases.

To further solidify their claim, this study worked in conjunction with their previous ones and accentuated everything. However, the ones done in the past led to undesirable side-effects. What made the major difference this time is the application of highly precise and specific equipment, something that wasn’t in the application before.

This new onset of discovery has a lot of potentials. However, human trials are still a far-fetched reality. There are still a few complications that must be resolved. Nonetheless, with the rate that the scientific world is progressing at, a permanent solution isn’t that far off.

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